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Our Research Programs

Cancer and Signal Transduction

Faculty and research interests:

Kenneth L. Byron, PhD - Signal transduction and ion channel regulation in vascular smooth muscle.

Neil Clipstone, PhD - The role of the calcineurin/NFAT-signaling pathway in cell growth and differentiation.

Michael Collins, PhD - Mediators/mechanisms of neurodegeneration and neuroprotection.

Mitchell Denning, PhD - Role of protein kinase C isoforms in normal skin biology, the response of skin to ultraviolet radiation, and skin carcinogenesis.

William Simmons, PhD - Mechanism of inactivation of bradykinin, an important hormone in the cardiovascular system.

Cardiovascular Pharmacology

Faculty and research interests:

Kenneth L. Byron, PhD - Signal transduction and ion channel regulation in vascular smooth muscle.

Jawed Fareed, PhD - Pharmacology of drugs used in the treatment of thrombosis and bleeding disorders.

Debra Hoppensteadt, PhD - Discovery of new anticoagulants used to treat thrombosis.

Walter K. Jones, PhD - Mechanism of ischemia reperfusion injury and cardioprotection in the role of stem cells, exosomes, and microRNAs in cardiovascular systems.

Karie Scrogin, PhD - Neuroendocrine regulation of circulation in shock, heart failure and anxiety.

William Simmons, PhD - Mechanism of inactivation of bradykinin, an important hormone in the cardiovascular system.

 

Neuropharmacology

Faculty and research interests:

Joanna Bakowska, PhD - Genetic, behavioral and cellular approaches to study mechanisms in spastic paraplegias.

Michael Collins, PhD - Mediators/mechanisms of neurodegeneration and neuroprotection.

Rocco Gogliotti, PhD - Neurogenetics of autism and autism-associated disorders and the neuropharmacology of novel treatment strategies.

Simon Kaja, PhD- Novel glioprotective and neuroprotective approaches for ocular disorders.

Gwendolyn Kartje, MD, PhD - Neuronal plasticity and recovery of function after stroke and traumatic brain injury.

Kelly Langert, PhD- Targeted drug delivery to the inflamed peripheral nerve, identifying novel therapeutic targets at the blood-nerve barrier and the leukocyte-endothelial interface, elucidating the physiological and pathophysiological roles of monomeric GTPases in endothelial cells.

Karie Scrogin, PhD - Neuroendocrine regulation of circulation in shock, heart failure and anxiety.

Monsheel Sodhi, PhD - Molecular mechanisms leading to CNS disorders, predictors of suicide risk and pharmacogenomic predictors of drug response.

RNA Therapeutics

Faculty and research interests:

W. Keith Jones, PhD - Exosomal RNA in Cardiovascular disease and regeneration.

Monsheel Sodhi, PhD - RNA editing in Neuropsychological disease.

Simon Kaja, PhD - Exosomes and miRNA in optic nerve biology.