Profiles
Jordan Beach, PhD
Assistant Professor
Contractile network dynamics
Education
- IRTA Post-doctoral Fellow, 2011-2017
- PhD Department of Physiology and Biophysics, 2004-2011
The Beach Lab is investigating how cells build contractile forces. These forces are critical at steady-state for many cellular processes, but are especially important during dynamic cell movements, such as cell migration and cell division. Our primary approach is to use high-resolution and super-resolution imaging techniques to determine how cells control the spatio-temporal assembly dynamics of myosin motor proteins.
Publications
- Bruun K*, Beach JR*, Remmert K, and Hammer JA. “Re-evaluating the roles of myosin 18Aα and F-actin in determining Golgi morphology” Cytoskeleton (Hoboken). 2017 Mar 22; PMID 28329908. *indicates equal contribution
- Beach JR, Kyle Bruun, Lin Shao, Dong Li, Zac Swider, Kirsten Remmert, Yingfang Zhang, Mary Anne Conti, Robert Adelstein, Nasser Rusan, Eric Betzig, John Hammer “Actin Dynamics and Competition for Myosin Monomer Govern the Sequential Amplification of Myosin Filaments”. Nat Cell Biol. 2017 Feb;19(2):85-93; PMID 28114272
- Beach JR and Hammer 3rd JA “Myosin II Coassembly and Isoform-Specificity in Mammalian Systems” Exp Cell Res. Review. 2015 May 15;334(1):2-9; PMID 25655283
- Billington N*, Beach JR*, Heissler SM, Guzik-Lendrum S, Nagy A, Takagi Y, Shao L, Li D, Remmert K, Yang Y, Barzik M, Betzig E, Hammer 3rd JA, Sellers JR “Myosin 18A Coassembles with Nonmuscle Myosin 2 to Form Mixed Bipolar Filaments” Curr Biol. 2015 Mar 30;25(7); PMID 25754640 *indicates equal contribution
- Beach JR*, Shao L, Remmert K, Li D, Betzig E, Hammer 3rd J* “Non-muscle Myosin II Isoforms Coassemble in Living Cells” Curr Biol. 2014 May 19; 24(10); PMID 24814144 *co-corresponding author
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