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Profiles

Kimberly E. Foreman, PhD

Associate Professor

Cancer Biology

Research Interests:

  • Research training
  • Medical education
  • Education outcomes

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Contact
  • CBCC 235
    • Education
    • BS in Microbiology, Miami University
    • PhD in Pathology and Immunology, University of Cincinnati
    • Fellowship in Endothelial Biology and Complement, University of Michigan
    • Fellowship in Viral Oncology, University of Michigan

    Although formally trained in immunology and cancer biology, Dr. Foreman’s interests have shifted toward education and the  need to introduce future physicians in the excitement of foundational and clinical research.  She currently serves as the Course Director for the first-year medical school course Molecular Cell Biology and Genetics and plays a key role in directing two NIH T35 training grants that support medical student research experiences.

    Research Interests

    • Research Training
    • Medical education
    • Education outcomes

    Publications

    • The role of cancer-derived exosomes in tumorigenicity & epithelial-to-mesenchymal transition  Blackwell, RH; Foreman, KE; Gupta, GN  Cancers (Basel)  2017 Aug 10;9(8):105. doi: 10.3390/cancers9080105. PMID: 28796150; PMCID: PMC5575608
    • Urinary exosomes: The potential for biomarker utility; intercellular signaling and therapeutics in urological malignancy  Franzen, CA; Blackwell, RH; Foreman, KE; Kuo, PC; Flanigan, RC; Gupta, GN  Journal of Urology  2016 May;195(5):1331-1339. doi:10.1016/j.juro.2015.08.115. Epub 2015 Dec 20. PMID: 26714199
    • Urothelial cells undergo epithelial-to-mesenchymal transition after exposure to muscle invasive bladder cancer exosomes  Franzen, CA; Blackwell, RH; Todorovic, V; Greco, KA; Foreman, KE; Flanigan, RC; Kuo, PC; Gupta, GN  Oncogenesis  2015 Aug 17;4(8):e163. doi: 10.1038/oncsis.2015.21. PMID: 26280654; PMCID: PMC4632072
    • Emetine dihydrochloride: a novel therapy for bladder cancer Foreman, KE; Jesse, JN 3rd; Kuo, PC; Gupta, GN  Journal of Urology  2014 Feb;191(2):502-9. doi: 10.1016/j.juro.2013.09.014. Epub 2013 Sep 14. PMID: 24045224
    • Targeting Notch to target cancer stem cells  Pannuti, A; Foreman, K; Rizzo, P; Osipo, C; Golde, T; Osborne, B; Miele, L  Clinical Cancer Research 2010 Jun 15;16(12):3141-52. doi: 10.1158/1078-0432.CCR-09-2823. Epub 2010 Jun 8. PMID: 20530696; PMCID: PMC3008160
    • Rational targeting of Notch signaling in cancer  Rizzo, P; Osipo, C; Foreman, K; Golde, T; Osborne, B; Miele, L  Oncogene  2008 Sep 1;27(38):5124-31. doi: 10.1038/onc.2008.226. PMID: 18758481
    • Notch inhibition in Kaposi's sarcoma tumor cells leads to mitotic catastrophe through nuclear factor-kappaB signaling  Curry, CL; Reed, LL; Broude, E; Golde, TE; Miele, L; Foreman, KE  Molecular Cancer Therapeutics  2007 Jul;6(7):1983-92. doi: 10.1158/1535-7163.MCT-07-0093. Epub 2007 Jun 29. PMID: 17604336
    • Gamma secretase inhibitor blocks Notch activation and induces apoptosis in Kaposi's sarcoma tumor cells  Curry, CL; Reed, LL; Golde, TE; Miele, L; Nickoloff, BJ; Foreman, KE  Oncogene  2005 Sep 22;24(42):6333-44. doi: 10.1038/sj.onc.1208783. PMID: 15940249
    • Lymphatic reprogramming of blood vascular endothelium by Kaposi sarcoma-associated herpesvirus  Hong, YK; Foreman, K; Shin, JW; Hirakawa, S; Curry, CL; Sage, DR; Libermann, T; Dezube, BJ; Fingeroth, JD; Detmar, M  Nature Genetics  2004 Jul;36(7):683-5. doi: 10.1038/ng1383. Epub 2004 Jun 27. PMID: 15220917
    • Propagation of a human herpesvirus from AIDS-associated Kaposi's sarcoma  Foreman, KE; Friborg, J Jr; Kong, WP; Woffendin, C; Polverini, PJ; Nickoloff, BJ; Nabel, GJ  New England Journal of Medicine 1997 Jan 16;336(3):163-71. doi: 10.1056/NEJM199701163360302. PMID: 8988896

    Additional Publications List